Transforming Growth Factor beta2

A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.

Also Known As:

BSC-1 Cell Growth Inhibitor; Cartilage-Inducing Factor-B; Glioblastoma-Derived T-Cell Suppressor Factor; Polyergin; Suppressor Factor, T-Cell, Glioblastoma-Derived; TGF-beta-2; TGF-beta2 Latency-Associated Protein; TGF-beta2LAP; Transforming Growth Factor beta 2 Latency Associated Peptide; BSC 1 Cell Growth Inhibitor; Cartilage Inducing Factor B; Glioblastoma Derived T Cell Suppressor Factor; Latency-Associated Protein, TGF-beta2; TGF beta2 Latency Associated Protein; TGF beta2LAP; TGF-beta2

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Transforming Growth Factor beta: 13953
        Transforming Growth Factor beta2: 307
    - TGF-beta Superfamily Proteins: 1
      - Transforming Growth Factor beta: 13953
        Transforming Growth Factor beta2: 307
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Transforming Growth Factor beta: 13953
        Transforming Growth Factor beta2: 307
    - TGF-beta Superfamily Proteins: 1
      - Transforming Growth Factor beta: 13953
        Transforming Growth Factor beta2: 307
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Cytokines: 164289
    - Transforming Growth Factor beta: 13953
      - Transforming Growth Factor beta2: 307
  - TGF-beta Superfamily Proteins: 1
    - Transforming Growth Factor beta: 13953
      - Transforming Growth Factor beta2: 307

R Dougherty Selected Research

R Dougherty Research Topics

Disease

Drug/Important Bio-Agent (IBA)